Pure Herbs herbal extracts historically used to support the Integumentary System, which is primarily the skin, also includes hair and nails. It provides protection from the outside world. The Integumentary System, or skin, is the body’s largest organ. It protects us from damage that can come from the outside world. The skin also helps to regulate body temperature and eliminates waste through perspiration; it has sensory receptors to detect pain, pressure, temperature and different sensations. In addition to the skin, the Integumentary system includes hair, nails and sweat glands.